Search for: All records

ABSTRACT Follow-up observations of neutrino events have been a promising method for identifying sources of very-high-energy cosmic rays. Neutrinos are unambiguous tracers of hadronic interactions and cosmic rays. On 2020 June 15, IceCube detected a neutrino event with an 82.8 per cent probability of being astrophysical in origin. To identify the astrophysical source of the neutrino, we used X-ray tiling observations to identify potential counterpart sources. We performed additional multiwavelength follow-up with NuSTAR and the VLA in order to construct a broadband spectral energy distribution (SED) of the most likely counterpart. From the SED, we calculate an estimate for the neutrinos we expect to detect from the source. While the source does not have a high predicted neutrino flux, it is still a plausible neutrino emitter. It is important to note that the other bright X-ray candidate sources consistent with the neutrino event are also radio-quiet active galactic nuclei. A statistical analysis shows that 1RXS J093117.6+033146 is the most likely counterpart (87.5 per cent) if the neutrino is cosmic in origin and if it is among X-ray detectable sources. This result adds to previous results suggesting a connection between radio-quiet AGN and IceCube neutrino events. 

Abstract We make an in-depth analysis of different active galactic nuclei (AGN) jet models’ signatures, inducing quiescence in galaxies with a halo mass of 10¹²M_⊙. Three jet models, including cosmic-ray-dominant, hot thermal, and precessing kinetic jets, are studied at two energy flux levels each, compared to a jet-free, stellar feedback-only simulation. Each of our simulations is idealized isolated galaxy simulations with AGN jet powers that are constant in time and generated using GIZMO and with FIRE stellar feedback. We examine the distribution of Mgii, Ovi, and Oviiiions, alongside gas temperature and density profiles. Low-energy ions, like Mgii, concentrate in the interstellar medium (ISM), while higher energy ions, e.g., Oviii, prevail at the AGN jet cocoon’s edge. High-energy flux jets display an isotropic ion distribution with lower overall density. High-energy thermal or cosmic-ray jets pressurize at smaller radii, significantly suppressing core density. The cosmic-ray jet provides extra pressure support, extending cool and warm gas distribution. A break in the ion-to-mass ratio slope in Oviand Oviiiis demonstrated in the ISM-to-circumgalactic medium (CGM) transition (between 10 and 30 kpc), growing smoothly toward the CGM at greater distances. 

Abstract With the aim of analyzing large-sized multidimensional single-cell datasets, we are describing a method for Cosine-based Tanimoto similarity-refined graph for community detection using Leiden’s algorithm (CosTaL). As a graph-based clustering method, CosTaL transforms the cells with high-dimensional features into a weighted k-nearest-neighbor (kNN) graph. The cells are represented by the vertices of the graph, while an edge between two vertices in the graph represents the close relatedness between the two cells. Specifically, CosTaL builds an exact kNN graph using cosine similarity and uses the Tanimoto coefficient as the refining strategy to re-weight the edges in order to improve the effectiveness of clustering. We demonstrate that CosTaL generally achieves equivalent or higher effectiveness scores on seven benchmark cytometry datasets and six single-cell RNA-sequencing datasets using six different evaluation metrics, compared with other state-of-the-art graph-based clustering methods, including PhenoGraph, Scanpy and PARC. As indicated by the combined evaluation metrics, Costal has high efficiency with small datasets and acceptable scalability for large datasets, which is beneficial for large-scale analysis. 

Abstract Identifying the sites of r-process nucleosynthesis, a primary mechanism of heavy element production, is a key goal of astrophysics. The discovery of the brightest gamma-ray burst (GRB) to date, GRB 221009A, presented an opportunity to spectroscopically test the idea that r-process elements are produced following the collapse of rapidly rotating massive stars. Here we present James Webb Space Telescope observations of GRB 221009A obtained +168 and +170 rest-frame days after the gamma-ray trigger, and demonstrate that they are well described by a SN 1998bw-like supernova (SN) and power-law afterglow, with no evidence for a component from r-process emission. The SN, with a nickel mass of approximately 0.09 M_⊙, is only slightly fainter than the brightness of SN 1998bw at this phase, which indicates that the SN is not an unusual GRB-SN. This demonstrates that the GRB and SN mechanisms are decoupled and that highly energetic GRBs are not likely to produce significant quantities of r-process material, which leaves open the question of whether explosions of massive stars are key sources of r-process elements. Moreover, the host galaxy of GRB 221009A has a very low metallicity of approximately 0.12 Z_⊙and strong H₂emission at the explosion site, which is consistent with recent star formation, hinting that environmental factors are responsible for its extreme energetics. 

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms, whereas viremia peaked within 1 week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. Remdesivir treatment was associated with faster viral decay.